E204-0137 Screening compound: 1-(6-{[4-(2-pyridyl)piperazino]sulfonyl}-2,3-dihydro-4H-1,4-benzoxazin-4-yl)-1-ethanone

E204-0137 Screening compound: 1-(6-{[4-(2-pyridyl)piperazino]sulfonyl}-2,3-dihydro-4H-1,4-benzoxazin-4-yl)-1-ethanone
E204-0137 Screening compound: 1-(6-{[4-(2-pyridyl)piperazino]sulfonyl}-2,3-dihydro-4H-1,4-benzoxazin-4-yl)-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound E204-0137
1-(6-{[4-(2-pyridyl)piperazino]sulfonyl}-2,3-dihydro-4H-1,4-benzoxazin-4-yl)-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E204-0137

Molecular Formula

C19H22N4O4S (C19 H22 N4 O4 S)

Compound Name

1-(6-{[4-(2-pyridyl)piperazino]sulfonyl}-2,3-dihydro-4H-1,4-benzoxazin-4-yl)-1-ethanone

IUPAC name

n/a

SMILES

CC(N1c(cc(cc2)S(N(CC3)CCN3c3ncccc3)(=O)=O)c2OCC1)=O

InChI

InChI=1S/C19H22N4O4S/c1-15(24)23-12-13-27-18-6-5-16(14-17(18)23)28(25,26)22-10-8-21(9-11-22)19-4-2-3-7-20-19/h2-7,14H,8-13H2,1H3

InChI Key

RKEIIVZULQUROL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14845804

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.097

Distribution Coefficient, logD

2.073

Water Solubility, LogSw

-2.67

Polar Surface Area

67.725

Acid Dissociation Constant (pKa)

23.05

Base Dissociation Constant (pKb)

6.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

E204-0137 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Purinergic Library (3321 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
  • Metabolic
Targets:
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E204-0137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E204-0137?
Check Price and Availability of E204-0137, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E204-0137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E204-0137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E204-0137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E204-0137 available by request