E207-1424 Screening compound: 3-{[4-(4-chlorophenyl)piperazino]carbonyl}-1-methyl-1,4-dihydro-5H-5lambda~6~-thiochromeno[4,3-c]pyrazole-5,5-dione

E207-1424 Screening compound: 3-{[4-(4-chlorophenyl)piperazino]carbonyl}-1-methyl-1,4-dihydro-5H-5lambda~6~-thiochromeno[4,3-c]pyrazole-5,5-dione
E207-1424 Screening compound: 3-{[4-(4-chlorophenyl)piperazino]carbonyl}-1-methyl-1,4-dihydro-5H-5lambda~6~-thiochromeno[4,3-c]pyrazole-5,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound E207-1424
3-{[4-(4-chlorophenyl)piperazino]carbonyl}-1-methyl-1,4-dihydro-5H-5lambda~6~-thiochromeno[4,3-c]pyrazole-5,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E207-1424

Molecular Formula

C22H21ClN4O3S (C22 H21 ClN4 O3 S)

Compound Name

3-{[4-(4-chlorophenyl)piperazino]carbonyl}-1-methyl-1,4-dihydro-5H-5lambda~6~-thiochromeno[4,3-c]pyrazole-5,5-dione

IUPAC name

3-[4-(4-chlorophenyl)piperazine-1-carbonyl]-1-methyl-1H4H-5lambda6-thiochromeno[43-c]pyrazole-55-dione

SMILES

Cn1nc(C(N(CC2)CCN2c(cc2)ccc2Cl)=O)c(C2)c1-c(cccc1)c1S2(=O)=O

InChI

InChI=1S/C22H21ClN4O3S/c1-25-21-17-4-2-3-5-19(17)31(29,30)14-18(21)20(24-25)22(28)27-12-10-26(11-13-27)16-8-6-15(23)7-9-16/h2-9H,10-14H2,1H3

InChI Key

KLUKPJBRNFUUJI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14846380

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.95

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.810

Distribution Coefficient, logD

2.810

Water Solubility, LogSw

-3.62

Polar Surface Area

62.996

Acid Dissociation Constant (pKa)

13.31

Base Dissociation Constant (pKb)

5.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

E207-1424 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-infective Library (19449 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E207-1424 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E207-1424?
Check Price and Availability of E207-1424, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E207-1424 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E207-1424
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E207-1424
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E207-1424 available by request