E209-0743 Screening compound: 2-{4-[(2-methoxyphenyl)methyl]-2,3-dioxo-1,2,3,4-tetrahydropyrazin-1-yl}-N-(2,4,6-trimethylphenyl)acetamide

E209-0743 Screening compound: 2-{4-[(2-methoxyphenyl)methyl]-2,3-dioxo-1,2,3,4-tetrahydropyrazin-1-yl}-N-(2,4,6-trimethylphenyl)acetamide
E209-0743 Screening compound: 2-{4-[(2-methoxyphenyl)methyl]-2,3-dioxo-1,2,3,4-tetrahydropyrazin-1-yl}-N-(2,4,6-trimethylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E209-0743
2-{4-[(2-methoxyphenyl)methyl]-2,3-dioxo-1,2,3,4-tetrahydropyrazin-1-yl}-N-(2,4,6-trimethylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E209-0743

Molecular Formula

C23H25N3O4 (C23 H25 N3 O4)

Compound Name

2-{4-[(2-methoxyphenyl)methyl]-2,3-dioxo-1,2,3,4-tetrahydropyrazin-1-yl}-N-(2,4,6-trimethylphenyl)acetamide

IUPAC name

2-{4-[(2-methoxyphenyl)methyl]-23-dioxo-1234-tetrahydropyrazin-1-yl}-N-(246-trimethylphenyl)acetamide

SMILES

Cc(cc1C)cc(C)c1NC(CN(C=CN(Cc(cccc1)c1OC)C1=O)C1=O)=O

InChI

InChI=1S/C23H25N3O4/c1-15-11-16(2)21(17(3)12-15)24-20(27)14-26-10-9-25(22(28)23(26)29)13-18-7-5-6-8-19(18)30-4/h5-12H,13-14H2,1-4H3,(H,24,27)

InChI Key

KSHVIHDCWFVCLF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14846735

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.977

Distribution Coefficient, logD

1.977

Water Solubility, LogSw

-2.54

Polar Surface Area

60.859

Acid Dissociation Constant (pKa)

12.29

Base Dissociation Constant (pKb)

-2.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

E209-0743 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with E209-0743 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E209-0743?
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What is the minimum amount of E209-0743 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E209-0743
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E209-0743
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E209-0743 available by request