E214-0106 Screening compound: N-(4-bromo-3-methylphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide

E214-0106 Screening compound: N-(4-bromo-3-methylphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
E214-0106 Screening compound: N-(4-bromo-3-methylphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E214-0106
N-(4-bromo-3-methylphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E214-0106

Molecular Formula

C12H12BrN3O4S (C12 H12 BrN3 O4 S)

Compound Name

N-(4-bromo-3-methylphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide

IUPAC name

N-(4-bromo-3-methylphenyl)-6-methyl-24-dioxo-1234-tetrahydropyrimidine-5-sulfonamide

SMILES

Cc(cc(cc1)NS(C(C(N2)=O)=C(C)NC2=O)(=O)=O)c1Br

InChI

InChI=1S/C12H12BrN3O4S/c1-6-5-8(3-4-9(6)13)16-21(19,20)10-7(2)14-12(18)15-11(10)17/h3-5,16H,1-2H3,(H2,14,15,17,18)

InChI Key

FRXDLLDPQIYSRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14847627

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.22

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.695

Distribution Coefficient, logD

-1.056

Water Solubility, LogSw

-2.51

Polar Surface Area

89.422

Acid Dissociation Constant (pKa)

4.65

Base Dissociation Constant (pKb)

-7.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

E214-0106 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Antibacterial Compounds Library (13827 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Proteases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E214-0106 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E214-0106?
Check Price and Availability of E214-0106, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E214-0106 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E214-0106
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E214-0106
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E214-0106 available by request