E228-0186 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide

E228-0186 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide
E228-0186 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E228-0186
N-(3-chloro-4-methoxyphenyl)-2-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E228-0186

Molecular Formula

C20H16ClN3O3 (C20 H16 ClN3 O3)

Compound Name

N-(3-chloro-4-methoxyphenyl)-2-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide

IUPAC name

N-(3-chloro-4-methoxyphenyl)-2-{4-oxo-4H5H-pyrrolo[12-a]quinoxalin-5-yl}acetamide

SMILES

COc(ccc(NC(CN(c(cccc1)c1-n1c2ccc1)C2=O)=O)c1)c1Cl

InChI

InChI=1S/C20H16ClN3O3/c1-27-18-9-8-13(11-14(18)21)22-19(25)12-24-16-6-3-2-5-15(16)23-10-4-7-17(23)20(24)26/h2-11H,12H2,1H3,(H,22,25)

InChI Key

XEKGFRAKRFAMEI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14849757

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.82

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.873

Distribution Coefficient, logD

3.872

Water Solubility, LogSw

-4.23

Polar Surface Area

47.745

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

1.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

E228-0186 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antimitotic Tubulin Library (17355 compounds)

Antiviral Annotated Library (21441 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with E228-0186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E228-0186?
Check Price and Availability of E228-0186, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E228-0186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E228-0186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E228-0186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E228-0186 available by request