E228-1467 Screening compound: N-[2-(2,4-dimethoxyphenyl)ethyl]-4-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide

E228-1467 Screening compound: N-[2-(2,4-dimethoxyphenyl)ethyl]-4-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide
E228-1467 Screening compound: N-[2-(2,4-dimethoxyphenyl)ethyl]-4-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E228-1467
N-[2-(2,4-dimethoxyphenyl)ethyl]-4-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E228-1467

Molecular Formula

C25H27N3O4 (C25 H27 N3 O4)

Compound Name

N-[2-(2,4-dimethoxyphenyl)ethyl]-4-{4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide

IUPAC name

N-[2-(24-dimethoxyphenyl)ethyl]-4-{4-oxo-4H5H-pyrrolo[12-a]quinoxalin-5-yl}butanamide

SMILES

COc1cc(OC)c(CCNC(CCCN(c(cccc2)c2-n2c3ccc2)C3=O)=O)cc1

InChI

InChI=1S/C25H27N3O4/c1-31-19-12-11-18(23(17-19)32-2)13-14-26-24(29)10-6-16-28-21-8-4-3-7-20(21)27-15-5-9-22(27)25(28)30/h3-5,7-9,11-12,15,17H,6,10,13-14,16H2,1-2H3,(H,26,29)

InChI Key

MEIGUUWJJNDBFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14849929

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.944

Distribution Coefficient, logD

2.944

Water Solubility, LogSw

-3.46

Polar Surface Area

56.431

Acid Dissociation Constant (pKa)

14.38

Base Dissociation Constant (pKb)

2.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

E228-1467 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with E228-1467 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E228-1467?
Check Price and Availability of E228-1467, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E228-1467 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E228-1467
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E228-1467
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E228-1467 available by request