E228-1728 Screening compound: N-[2-(4-ethoxyphenyl)ethyl]-2-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide

E228-1728 Screening compound: N-[2-(4-ethoxyphenyl)ethyl]-2-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide
E228-1728 Screening compound: N-[2-(4-ethoxyphenyl)ethyl]-2-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E228-1728
N-[2-(4-ethoxyphenyl)ethyl]-2-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E228-1728

Molecular Formula

C23H22FN3O3 (C23 H22 FN3 O3)

Compound Name

N-[2-(4-ethoxyphenyl)ethyl]-2-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}acetamide

IUPAC name

N-[2-(4-ethoxyphenyl)ethyl]-2-{7-fluoro-4-oxo-4H5H-pyrrolo[12-a]quinoxalin-5-yl}acetamide

SMILES

CCOc1ccc(CCNC(CN(c(cc(cc2)F)c2-n2c3ccc2)C3=O)=O)cc1

InChI

InChI=1S/C23H22FN3O3/c1-2-30-18-8-5-16(6-9-18)11-12-25-22(28)15-27-21-14-17(24)7-10-19(21)26-13-3-4-20(26)23(27)29/h3-10,13-14H,2,11-12,15H2,1H3,(H,25,28)

InChI Key

WAQIMVYVJNNBJV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850022

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.174

Distribution Coefficient, logD

3.174

Water Solubility, LogSw

-3.38

Polar Surface Area

48.402

Acid Dissociation Constant (pKa)

14.57

Base Dissociation Constant (pKb)

3.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

E228-1728 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with E228-1728 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E228-1728?
Check Price and Availability of E228-1728, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E228-1728 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E228-1728
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E228-1728
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E228-1728 available by request