E228-1775 Screening compound: 5-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-7-fluoro-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one

E228-1775 Screening compound: 5-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-7-fluoro-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one
E228-1775 Screening compound: 5-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-7-fluoro-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E228-1775
5-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-7-fluoro-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E228-1775

Molecular Formula

C25H25FN4O2 (C25 H25 FN4 O2)

Compound Name

5-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-7-fluoro-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one

IUPAC name

5-{2-[4-(25-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-7-fluoro-4H5H-pyrrolo[12-a]quinoxalin-4-one

SMILES

Cc1cc(N(CC2)CCN2C(CN(c(cc(cc2)F)c2-n2c3ccc2)C3=O)=O)c(C)cc1

InChI

InChI=1S/C25H25FN4O2/c1-17-5-6-18(2)22(14-17)27-10-12-28(13-11-27)24(31)16-30-23-15-19(26)7-8-20(23)29-9-3-4-21(29)25(30)32/h3-9,14-15H,10-13,16H2,1-2H3

InChI Key

FPXINNNKSAUPMZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850038

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.175

Distribution Coefficient, logD

4.175

Water Solubility, LogSw

-4.24

Polar Surface Area

36.317

Acid Dissociation Constant (pKa)

22.47

Base Dissociation Constant (pKb)

4.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

E228-1775 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antiviral Annotated Library (21441 compounds)

Antiviral Library (67538 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with E228-1775 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E228-1775?
Check Price and Availability of E228-1775, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E228-1775 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E228-1775
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E228-1775
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E228-1775 available by request