E230-0624 Screening compound: 4-{1-[(4-methylphenyl)methyl]-1H-indol-3-yl}-1-(pyrrolidin-1-yl)butan-1-one

E230-0624 Screening compound: 4-{1-[(4-methylphenyl)methyl]-1H-indol-3-yl}-1-(pyrrolidin-1-yl)butan-1-one
E230-0624 Screening compound: 4-{1-[(4-methylphenyl)methyl]-1H-indol-3-yl}-1-(pyrrolidin-1-yl)butan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E230-0624
4-{1-[(4-methylphenyl)methyl]-1H-indol-3-yl}-1-(pyrrolidin-1-yl)butan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E230-0624

Molecular Formula

C24H28N2O (C24 H28 N2 O)

Compound Name

4-{1-[(4-methylphenyl)methyl]-1H-indol-3-yl}-1-(pyrrolidin-1-yl)butan-1-one

IUPAC name

4-{1-[(4-methylphenyl)methyl]-1H-indol-3-yl}-1-(pyrrolidin-1-yl)butan-1-one

SMILES

Cc1ccc(Cn2c(cccc3)c3c(CCCC(N3CCCC3)=O)c2)cc1

InChI

InChI=1S/C24H28N2O/c1-19-11-13-20(14-12-19)17-26-18-21(22-8-2-3-9-23(22)26)7-6-10-24(27)25-15-4-5-16-25/h2-3,8-9,11-14,18H,4-7,10,15-17H2,1H3

InChI Key

NPCGAPXEWYZDLN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850523

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.5

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.775

Distribution Coefficient, logD

4.775

Water Solubility, LogSw

-4.65

Polar Surface Area

18.457

Acid Dissociation Constant (pKa)

22.47

Base Dissociation Constant (pKb)

-1.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

E230-0624 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E230-0624 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E230-0624?
Check Price and Availability of E230-0624, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E230-0624 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E230-0624
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E230-0624
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E230-0624 available by request