E233-0719 Screening compound: 2-ethyl-N-(4-fluorophenyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazole-7-carboxamide

E233-0719 Screening compound: 2-ethyl-N-(4-fluorophenyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazole-7-carboxamide
E233-0719 Screening compound: 2-ethyl-N-(4-fluorophenyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazole-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E233-0719
2-ethyl-N-(4-fluorophenyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazole-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E233-0719

Molecular Formula

C19H18FN3O2 (C19 H18 FN3 O2)

Compound Name

2-ethyl-N-(4-fluorophenyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazole-7-carboxamide

IUPAC name

2-ethyl-N-(4-fluorophenyl)-8-methyl-2H4H5H-furo[23-g]indazole-7-carboxamide

SMILES

CCn(cc1CC2)nc1-c1c2oc(C(Nc(cc2)ccc2F)=O)c1C

InChI

InChI=1S/C19H18FN3O2/c1-3-23-10-12-4-9-15-16(17(12)22-23)11(2)18(25-15)19(24)21-14-7-5-13(20)6-8-14/h5-8,10H,3-4,9H2,1-2H3,(H,21,24)

InChI Key

WIHMGSFHOJITJO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850571

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

339.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.371

Distribution Coefficient, logD

3.370

Water Solubility, LogSw

-3.48

Polar Surface Area

46.924

Acid Dissociation Constant (pKa)

9.99

Base Dissociation Constant (pKb)

-0.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.32

E233-0719 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with E233-0719 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E233-0719?
Check Price and Availability of E233-0719, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E233-0719 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E233-0719
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E233-0719
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E233-0719 available by request