E233-2139 Screening compound: 2-[(2-chloro-6-fluorophenyl)methyl]-N-(3-methoxyphenyl)-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carboxamide

E233-2139 Screening compound: 2-[(2-chloro-6-fluorophenyl)methyl]-N-(3-methoxyphenyl)-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carboxamide
E233-2139 Screening compound: 2-[(2-chloro-6-fluorophenyl)methyl]-N-(3-methoxyphenyl)-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E233-2139
2-[(2-chloro-6-fluorophenyl)methyl]-N-(3-methoxyphenyl)-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E233-2139

Molecular Formula

C25H21ClFN3O3 (C25 H21 ClFN3 O3)

Compound Name

2-[(2-chloro-6-fluorophenyl)methyl]-N-(3-methoxyphenyl)-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carboxamide

IUPAC name

2-[(2-chloro-6-fluorophenyl)methyl]-N-(3-methoxyphenyl)-8-methyl-2H4H5H-furo[23-g]indazole-7-carboxamide

SMILES

Cc1c(C(Nc2cc(OC)ccc2)=O)oc2c1-c1nn(Cc(c(F)ccc3)c3Cl)cc1CC2

InChI

InChI=1S/C25H21ClFN3O3/c1-14-22-21(33-24(14)25(31)28-16-5-3-6-17(11-16)32-2)10-9-15-12-30(29-23(15)22)13-18-19(26)7-4-8-20(18)27/h3-8,11-12H,9-10,13H2,1-2H3,(H,28,31)

InChI Key

ZFJILUCSMZKSMU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850728

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.91

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.280

Distribution Coefficient, logD

5.280

Water Solubility, LogSw

-6.08

Polar Surface Area

54.471

Acid Dissociation Constant (pKa)

10.81

Base Dissociation Constant (pKb)

-1.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

E233-2139 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E233-2139 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E233-2139?
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What is the minimum amount of E233-2139 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E233-2139
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E233-2139
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E233-2139 available by request