E235-0373 Screening compound: N~7~-(2-fluorophenyl)-2-(4-methoxyphenyl)imidazo[2,1-b][1,3]benzothiazole-7-carboxamide

E235-0373 Screening compound: N~7~-(2-fluorophenyl)-2-(4-methoxyphenyl)imidazo[2,1-b][1,3]benzothiazole-7-carboxamide
E235-0373 Screening compound: N~7~-(2-fluorophenyl)-2-(4-methoxyphenyl)imidazo[2,1-b][1,3]benzothiazole-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E235-0373
N~7~-(2-fluorophenyl)-2-(4-methoxyphenyl)imidazo[2,1-b][1,3]benzothiazole-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E235-0373

Molecular Formula

C23H16FN3O2S (C23 H16 FN3 O2 S)

Compound Name

N~7~-(2-fluorophenyl)-2-(4-methoxyphenyl)imidazo[2,1-b][1,3]benzothiazole-7-carboxamide

IUPAC name

N-(2-fluorophenyl)-4-(4-methoxyphenyl)-7-thia-25-diazatricyclo[6.4.0.0^{26}]dodeca-1(12)35810-pentaene-10-carboxamide

SMILES

COc(cc1)ccc1-c1cn(c(ccc(C(Nc(cccc2)c2F)=O)c2)c2s2)c2n1

InChI

InChI=1S/C23H16FN3O2S/c1-29-16-9-6-14(7-10-16)19-13-27-20-11-8-15(12-21(20)30-23(27)26-19)22(28)25-18-5-3-2-4-17(18)24/h2-13H,1H3,(H,25,28)

InChI Key

UZPDKRFTBZIQLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14851428

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.344

Distribution Coefficient, logD

5.323

Water Solubility, LogSw

-5.28

Polar Surface Area

38.882

Acid Dissociation Constant (pKa)

9.61

Base Dissociation Constant (pKb)

6.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

E235-0373 in Drug Discovery

Included in Screening Libraries

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E235-0373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E235-0373?
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What is the minimum amount of E235-0373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E235-0373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E235-0373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E235-0373 available by request