E238-0245 Screening compound: 7-(4-chlorophenyl)-N-(4-ethoxyphenyl)-5-(3-methoxyphenyl)-4H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide

E238-0245 Screening compound: 7-(4-chlorophenyl)-N-(4-ethoxyphenyl)-5-(3-methoxyphenyl)-4H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide
E238-0245 Screening compound: 7-(4-chlorophenyl)-N-(4-ethoxyphenyl)-5-(3-methoxyphenyl)-4H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E238-0245
7-(4-chlorophenyl)-N-(4-ethoxyphenyl)-5-(3-methoxyphenyl)-4H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E238-0245

Molecular Formula

C28H25ClN4O3 (C28 H25 ClN4 O3)

Compound Name

7-(4-chlorophenyl)-N-(4-ethoxyphenyl)-5-(3-methoxyphenyl)-4H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide

IUPAC name

7-(4-chlorophenyl)-N-(4-ethoxyphenyl)-5-(3-methoxyphenyl)-4H7H-pyrazolo[15-a]pyrimidine-3-carboxamide

SMILES

CCOc(cc1)ccc1NC(c1c(NC(c2cc(OC)ccc2)=CC2c(cc3)ccc3Cl)n2nc1)=O

InChI

InChI=1S/C28H25ClN4O3/c1-3-36-22-13-11-21(12-14-22)31-28(34)24-17-30-33-26(18-7-9-20(29)10-8-18)16-25(32-27(24)33)19-5-4-6-23(15-19)35-2/h4-17,26,32H,3H2,1-2H3,(H,31,34)/t26-/m0/s1

InChI Key

RNOPKHWPLRHVCZ-SANMLTNESA-N

MDL Number (MFCD)

MFCD14851930

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

500.98

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.319

Distribution Coefficient, logD

6.319

Water Solubility, LogSw

-6.26

Polar Surface Area

62.532

Acid Dissociation Constant (pKa)

10.87

Base Dissociation Constant (pKb)

-1.21

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

14.30

E238-0245 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E238-0245 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E238-0245?
Check Price and Availability of E238-0245, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E238-0245 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E238-0245
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E238-0245
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E238-0245 available by request