E240-0468 Screening compound: N-[(adamantan-1-yl)methyl]-3-(2-hydroxyphenyl)-1,2-oxazole-5-carboxamide

E240-0468 Screening compound: N-[(adamantan-1-yl)methyl]-3-(2-hydroxyphenyl)-1,2-oxazole-5-carboxamide
E240-0468 Screening compound: N-[(adamantan-1-yl)methyl]-3-(2-hydroxyphenyl)-1,2-oxazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E240-0468
N-[(adamantan-1-yl)methyl]-3-(2-hydroxyphenyl)-1,2-oxazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E240-0468

Molecular Formula

C21H24N2O3 (C21 H24 N2 O3)

Compound Name

N-[(adamantan-1-yl)methyl]-3-(2-hydroxyphenyl)-1,2-oxazole-5-carboxamide

IUPAC name

N-[(adamantan-1-yl)methyl]-3-(2-hydroxyphenyl)-12-oxazole-5-carboxamide

SMILES

Oc(cccc1)c1-c1noc(C(NCC2(CC(C3)C4)CC4CC3C2)=O)c1

InChI

InChI=1S/C21H24N2O3/c24-18-4-2-1-3-16(18)17-8-19(26-23-17)20(25)22-12-21-9-13-5-14(10-21)7-15(6-13)11-21/h1-4,8,13-15,24H,5-7,9-12H2,(H,22,25)

InChI Key

FUAHPCLEJVJQGL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08106805

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.342

Distribution Coefficient, logD

5.311

Water Solubility, LogSw

-5.41

Polar Surface Area

62.768

Acid Dissociation Constant (pKa)

8.54

Base Dissociation Constant (pKb)

-1.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.40

E240-0468 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with E240-0468 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E240-0468?
Check Price and Availability of E240-0468, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E240-0468 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E240-0468
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E240-0468
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E240-0468 available by request