E456-1365 Screening compound: N-(2-methoxyphenyl)-2-(4-methoxyphenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide

E456-1365 Screening compound: N-(2-methoxyphenyl)-2-(4-methoxyphenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
E456-1365 Screening compound: N-(2-methoxyphenyl)-2-(4-methoxyphenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E456-1365
N-(2-methoxyphenyl)-2-(4-methoxyphenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E456-1365

Molecular Formula

C24H20N2O4 (C24 H20 N2 O4)

Compound Name

N-(2-methoxyphenyl)-2-(4-methoxyphenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide

IUPAC name

N-(2-methoxyphenyl)-2-(4-methoxyphenyl)-1-oxo-12-dihydroisoquinoline-4-carboxamide

SMILES

COc(cc1)ccc1N(C=C(C(Nc(cccc1)c1OC)=O)c1c2cccc1)C2=O

InChI

InChI=1S/C24H20N2O4/c1-29-17-13-11-16(12-14-17)26-15-20(18-7-3-4-8-19(18)24(26)28)23(27)25-21-9-5-6-10-22(21)30-2/h3-15H,1-2H3,(H,25,27)

InChI Key

GYADURIFXDNVPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14853822

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.476

Distribution Coefficient, logD

3.472

Water Solubility, LogSw

-3.89

Polar Surface Area

53.322

Acid Dissociation Constant (pKa)

9.40

Base Dissociation Constant (pKb)

-1.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

E456-1365 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E456-1365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E456-1365?
Check Price and Availability of E456-1365, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E456-1365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E456-1365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E456-1365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E456-1365 available by request