E465-0532 Screening compound: N-(4-methoxyphenyl)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-sulfonamide

E465-0532 Screening compound: N-(4-methoxyphenyl)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-sulfonamide
E465-0532 Screening compound: N-(4-methoxyphenyl)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E465-0532
N-(4-methoxyphenyl)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E465-0532

Molecular Formula

C16H16N2O4S2 (C16 H16 N2 O4 S2)

Compound Name

N-(4-methoxyphenyl)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-sulfonamide

IUPAC name

N-(4-methoxyphenyl)-2-methyl-3-oxo-34-dihydro-2H-14-benzothiazine-6-sulfonamide

SMILES

CC1Sc(ccc(S(Nc(cc2)ccc2OC)(=O)=O)c2)c2NC1=O

InChI

InChI=1S/C16H16N2O4S2/c1-10-16(19)17-14-9-13(7-8-15(14)23-10)24(20,21)18-11-3-5-12(22-2)6-4-11/h3-10,18H,1-2H3,(H,17,19)/t10-/m1/s1

InChI Key

CQPGYEDZMKCTJA-SNVBAGLBSA-N

MDL Number (MFCD)

MFCD14854433

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.986

Distribution Coefficient, logD

2.936

Water Solubility, LogSw

-3.64

Polar Surface Area

73.309

Acid Dissociation Constant (pKa)

8.31

Base Dissociation Constant (pKb)

-4.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

18.80

E465-0532 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anti-Aging Library (44940 compounds)

Anti-Inflammatory Library (24602 compounds)

Antiviral Annotated Library (21441 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E465-0532 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E465-0532?
Check Price and Availability of E465-0532, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E465-0532 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E465-0532
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E465-0532
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E465-0532 available by request