E470-0371 Screening compound: ethyl 4-[(3,4-dioxo-2-phenylcyclobut-1-en-1-yl)amino]benzoate

E470-0371 Screening compound: ethyl 4-[(3,4-dioxo-2-phenylcyclobut-1-en-1-yl)amino]benzoate
E470-0371 Screening compound: ethyl 4-[(3,4-dioxo-2-phenylcyclobut-1-en-1-yl)amino]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound E470-0371
ethyl 4-[(3,4-dioxo-2-phenylcyclobut-1-en-1-yl)amino]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E470-0371

Molecular Formula

C19H15NO4 (C19 H15 NO4)

Compound Name

ethyl 4-[(3,4-dioxo-2-phenylcyclobut-1-en-1-yl)amino]benzoate

IUPAC name

ethyl 4-[(34-dioxo-2-phenylcyclobut-1-en-1-yl)amino]benzoate

SMILES

CCOC(c(cc1)ccc1NC(C(C1=O)=O)=C1c1ccccc1)=O

InChI

InChI=1S/C19H15NO4/c1-2-24-19(23)13-8-10-14(11-9-13)20-16-15(17(21)18(16)22)12-6-4-3-5-7-12/h3-11,20H,2H2,1H3

InChI Key

UWJHCGBJUJRSSV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14854686

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

321.33

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.679

Distribution Coefficient, logD

3.665

Water Solubility, LogSw

-3.85

Polar Surface Area

56.648

Acid Dissociation Constant (pKa)

8.89

Base Dissociation Constant (pKb)

0.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

E470-0371 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with E470-0371 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E470-0371?
Check Price and Availability of E470-0371, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E470-0371 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E470-0371
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E470-0371
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E470-0371 available by request