E470-1376 Screening compound: 4-acetyl-N-(2,4-difluorophenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide

E470-1376 Screening compound: 4-acetyl-N-(2,4-difluorophenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide
E470-1376 Screening compound: 4-acetyl-N-(2,4-difluorophenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E470-1376
4-acetyl-N-(2,4-difluorophenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E470-1376

Molecular Formula

C17H16F2N2O4S (C17 H16 F2 N2 O4 S)

Compound Name

4-acetyl-N-(2,4-difluorophenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide

IUPAC name

4-acetyl-N-(24-difluorophenyl)-6-methyl-34-dihydro-2H-14-benzoxazine-7-sulfonamide

SMILES

CC(N(CCOc1c2)c1cc(C)c2S(Nc(ccc(F)c1)c1F)(=O)=O)=O

InChI

InChI=1S/C17H16F2N2O4S/c1-10-7-15-16(25-6-5-21(15)11(2)22)9-17(10)26(23,24)20-14-4-3-12(18)8-13(14)19/h3-4,7-9,20H,5-6H2,1-2H3

InChI Key

WCFFXIGLFMHDAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14855035

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.39

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.687

Distribution Coefficient, logD

1.074

Water Solubility, LogSw

-3.08

Polar Surface Area

64.194

Acid Dissociation Constant (pKa)

5.80

Base Dissociation Constant (pKb)

-3.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

E470-1376 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with E470-1376 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E470-1376?
Check Price and Availability of E470-1376, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E470-1376 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E470-1376
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E470-1376
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E470-1376 available by request