E470-1459 Screening compound: 4-acetyl-N-(2-ethyl-6-methylphenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide

E470-1459 Screening compound: 4-acetyl-N-(2-ethyl-6-methylphenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide
E470-1459 Screening compound: 4-acetyl-N-(2-ethyl-6-methylphenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E470-1459
4-acetyl-N-(2-ethyl-6-methylphenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E470-1459

Molecular Formula

C20H24N2O4S (C20 H24 N2 O4 S)

Compound Name

4-acetyl-N-(2-ethyl-6-methylphenyl)-6-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide

IUPAC name

4-acetyl-N-(2-ethyl-6-methylphenyl)-6-methyl-34-dihydro-2H-14-benzoxazine-7-sulfonamide

SMILES

CCc(cccc1C)c1NS(c(cc1OCC2)c(C)cc1N2C(C)=O)(=O)=O

InChI

InChI=1S/C20H24N2O4S/c1-5-16-8-6-7-13(2)20(16)21-27(24,25)19-12-18-17(11-14(19)3)22(15(4)23)9-10-26-18/h6-8,11-12,21H,5,9-10H2,1-4H3

InChI Key

HZPBTCKJWUFFNN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14855051

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.280

Distribution Coefficient, logD

3.276

Water Solubility, LogSw

-3.46

Polar Surface Area

63.496

Acid Dissociation Constant (pKa)

9.45

Base Dissociation Constant (pKb)

-3.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

E470-1459 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E470-1459 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E470-1459?
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What is the minimum amount of E470-1459 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E470-1459
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E470-1459
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E470-1459 available by request