E512-0109 Screening compound: 2-[8-methyl-7-(morpholine-4-carbonyl)-2H,4H,5H-furo[2,3-g]indazol-2-yl]-N-(2-phenylethyl)acetamide

E512-0109 Screening compound: 2-[8-methyl-7-(morpholine-4-carbonyl)-2H,4H,5H-furo[2,3-g]indazol-2-yl]-N-(2-phenylethyl)acetamide
E512-0109 Screening compound: 2-[8-methyl-7-(morpholine-4-carbonyl)-2H,4H,5H-furo[2,3-g]indazol-2-yl]-N-(2-phenylethyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E512-0109
2-[8-methyl-7-(morpholine-4-carbonyl)-2H,4H,5H-furo[2,3-g]indazol-2-yl]-N-(2-phenylethyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E512-0109

Molecular Formula

C25H28N4O4 (C25 H28 N4 O4)

Compound Name

2-[8-methyl-7-(morpholine-4-carbonyl)-2H,4H,5H-furo[2,3-g]indazol-2-yl]-N-(2-phenylethyl)acetamide

IUPAC name

2-[8-methyl-7-(morpholine-4-carbonyl)-2H4H5H-furo[23-g]indazol-2-yl]-N-(2-phenylethyl)acetamide

SMILES

Cc1c(C(N2CCOCC2)=O)oc2c1-c1nn(CC(NCCc3ccccc3)=O)cc1CC2

InChI

InChI=1S/C25H28N4O4/c1-17-22-20(33-24(17)25(31)28-11-13-32-14-12-28)8-7-19-15-29(27-23(19)22)16-21(30)26-10-9-18-5-3-2-4-6-18/h2-6,15H,7-14,16H2,1H3,(H,26,30)

InChI Key

ZYFORVKCCCQIIK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14893280

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.793

Distribution Coefficient, logD

1.793

Water Solubility, LogSw

-2.09

Polar Surface Area

72.706

Acid Dissociation Constant (pKa)

14.63

Base Dissociation Constant (pKb)

-0.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

E512-0109 in Drug Discovery

Included in Screening Libraries

Lipid Metabolism Library (9174 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Immune system
  • animal
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E512-0109 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E512-0109?
Check Price and Availability of E512-0109, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E512-0109 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E512-0109
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E512-0109
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E512-0109 available by request