E521-1154 Screening compound: 4-[4-(morpholin-4-yl)-4-oxobutyl]-2-phenyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one

E521-1154 Screening compound: 4-[4-(morpholin-4-yl)-4-oxobutyl]-2-phenyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one
E521-1154 Screening compound: 4-[4-(morpholin-4-yl)-4-oxobutyl]-2-phenyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E521-1154
4-[4-(morpholin-4-yl)-4-oxobutyl]-2-phenyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E521-1154

Molecular Formula

C21H23N3O4 (C21 H23 N3 O4)

Compound Name

4-[4-(morpholin-4-yl)-4-oxobutyl]-2-phenyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one

IUPAC name

4-[4-(morpholin-4-yl)-4-oxobutyl]-2-phenyl-2H3H4H-pyrido[32-b][14]oxazin-3-one

SMILES

O=C(CCCN1c2ncccc2OC(c2ccccc2)C1=O)N1CCOCC1

InChI

InChI=1S/C21H23N3O4/c25-18(23-12-14-27-15-13-23)9-5-11-24-20-17(8-4-10-22-20)28-19(21(24)26)16-6-2-1-3-7-16/h1-4,6-8,10,19H,5,9,11-15H2/t19-/m0/s1

InChI Key

XVDBIGOLTUKPCH-IBGZPJMESA-N

MDL Number (MFCD)

MFCD14894354

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.298

Distribution Coefficient, logD

1.298

Water Solubility, LogSw

-1.49

Polar Surface Area

57.363

Acid Dissociation Constant (pKa)

17.59

Base Dissociation Constant (pKb)

-0.46

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

E521-1154 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E521-1154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E521-1154?
Check Price and Availability of E521-1154, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E521-1154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E521-1154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E521-1154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E521-1154 available by request