E524-0918 Screening compound: 5-[3-oxo-3-(1-pyrrolidinyl)propyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one

E524-0918 Screening compound: 5-[3-oxo-3-(1-pyrrolidinyl)propyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one
E524-0918 Screening compound: 5-[3-oxo-3-(1-pyrrolidinyl)propyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E524-0918
5-[3-oxo-3-(1-pyrrolidinyl)propyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E524-0918

Molecular Formula

C17H18N4O2 (C17 H18 N4 O2)

Compound Name

5-[3-oxo-3-(1-pyrrolidinyl)propyl]pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one

IUPAC name

8-[3-oxo-3-(pyrrolidin-1-yl)propyl]-2810-triazatricyclo[7.4.0.0^{26}]trideca-1(13)35911-pentaen-7-one

SMILES

O=C(CCN(C1=O)c2ncccc2-n2c1ccc2)N1CCCC1

InChI

InChI=1S/C17H18N4O2/c22-15(19-9-1-2-10-19)7-12-21-16-13(5-3-8-18-16)20-11-4-6-14(20)17(21)23/h3-6,8,11H,1-2,7,9-10,12H2

InChI Key

QKJSICKKWXABOQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14894802

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

310.36

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.691

Distribution Coefficient, logD

1.691

Water Solubility, LogSw

-1.71

Polar Surface Area

44.033

Acid Dissociation Constant (pKa)

23.71

Base Dissociation Constant (pKb)

2.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.30

E524-0918 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Soluble Diversity Library (15920 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E524-0918 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E524-0918?
Check Price and Availability of E524-0918, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E524-0918 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E524-0918
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E524-0918
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E524-0918 available by request