E524-1140 Screening compound: N~1~-[3-(4-benzylpiperidino)propyl]-3-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]propanamide

E524-1140 Screening compound: N~1~-[3-(4-benzylpiperidino)propyl]-3-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]propanamide
E524-1140 Screening compound: N~1~-[3-(4-benzylpiperidino)propyl]-3-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E524-1140
N~1~-[3-(4-benzylpiperidino)propyl]-3-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E524-1140

Molecular Formula

C28H33N5O2 (C28 H33 N5 O2)

Compound Name

N~1~-[3-(4-benzylpiperidino)propyl]-3-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]propanamide

IUPAC name

N-[3-(4-benzylpiperidin-1-yl)propyl]-3-{7-oxo-2810-triazatricyclo[7.4.0.0^{26}]trideca-1(13)35911-pentaen-8-yl}propanamide

SMILES

O=C(CCN(C1=O)c2ncccc2-n2c1ccc2)NCCCN1CCC(Cc2ccccc2)CC1

InChI

InChI=1S/C28H33N5O2/c34-26(13-20-33-27-24(9-4-14-30-27)32-17-5-10-25(32)28(33)35)29-15-6-16-31-18-11-23(12-19-31)21-22-7-2-1-3-8-22/h1-5,7-10,14,17,23H,6,11-13,15-16,18-21H2,(H,29,34)

InChI Key

VBNMAANJBNKVSH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14894938

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.638

Distribution Coefficient, logD

1.546

Water Solubility, LogSw

-3.89

Polar Surface Area

55.299

Acid Dissociation Constant (pKa)

15.05

Base Dissociation Constant (pKb)

9.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.30

E524-1140 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E524-1140 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E524-1140?
Check Price and Availability of E524-1140, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E524-1140 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E524-1140
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E524-1140
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E524-1140 available by request