E524-1766 Screening compound: N~1~-(2,4-dimethoxyphenethyl)-4-{[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]methyl}benzamide

E524-1766 Screening compound: N~1~-(2,4-dimethoxyphenethyl)-4-{[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]methyl}benzamide
E524-1766 Screening compound: N~1~-(2,4-dimethoxyphenethyl)-4-{[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]methyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E524-1766
N~1~-(2,4-dimethoxyphenethyl)-4-{[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]methyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E524-1766

Molecular Formula

C28H26N4O4 (C28 H26 N4 O4)

Compound Name

N~1~-(2,4-dimethoxyphenethyl)-4-{[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]methyl}benzamide

IUPAC name

N-[2-(24-dimethoxyphenyl)ethyl]-4-({7-oxo-2810-triazatricyclo[7.4.0.0^{26}]trideca-1(13)35911-pentaen-8-yl}methyl)benzamide

SMILES

COc1cc(OC)c(CCNC(c2ccc(CN(C3=O)c4ncccc4-n4c3ccc4)cc2)=O)cc1

InChI

InChI=1S/C28H26N4O4/c1-35-22-12-11-20(25(17-22)36-2)13-15-30-27(33)21-9-7-19(8-10-21)18-32-26-23(5-3-14-29-26)31-16-4-6-24(31)28(32)34/h3-12,14,16-17H,13,15,18H2,1-2H3,(H,30,33)

InChI Key

FWUPSRBJLNAVBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27599781

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.036

Distribution Coefficient, logD

4.036

Water Solubility, LogSw

-4.16

Polar Surface Area

66.725

Acid Dissociation Constant (pKa)

12.97

Base Dissociation Constant (pKb)

2.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.90

E524-1766 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with E524-1766 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E524-1766?
Check Price and Availability of E524-1766, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E524-1766 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E524-1766
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E524-1766
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E524-1766 available by request