E565-0090 Screening compound: 4-{3-[(4-methylphenyl)sulfonyl]thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-yl}morpholine

E565-0090 Screening compound: 4-{3-[(4-methylphenyl)sulfonyl]thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-yl}morpholine
E565-0090 Screening compound: 4-{3-[(4-methylphenyl)sulfonyl]thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-yl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound E565-0090
4-{3-[(4-methylphenyl)sulfonyl]thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-yl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E565-0090

Molecular Formula

C18H17N5O3S2 (C18 H17 N5 O3 S2)

Compound Name

4-{3-[(4-methylphenyl)sulfonyl]thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-yl}morpholine

IUPAC name

10-(4-methylbenzenesulfonyl)-7-(morpholin-4-yl)-5-thia-181112-tetraazatricyclo[7.3.0.0^{26}]dodeca-2(6)37911-pentaene

SMILES

Cc(cc1)ccc1S(c(nnn1c2c3scc2)c1nc3N1CCOCC1)(=O)=O

InChI

InChI=1S/C18H17N5O3S2/c1-12-2-4-13(5-3-12)28(24,25)18-17-19-16(22-7-9-26-10-8-22)15-14(6-11-27-15)23(17)21-20-18/h2-6,11H,7-10H2,1H3

InChI Key

JWJYTWHVRSWRAZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06744557

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.381

Distribution Coefficient, logD

3.381

Water Solubility, LogSw

-3.52

Polar Surface Area

74.055

Acid Dissociation Constant (pKa)

22.92

Base Dissociation Constant (pKb)

1.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

E565-0090 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

PI3K-Targeted Library (17255 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases

References: we are preparing a list of scientific research reports with E565-0090 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E565-0090?
Check Price and Availability of E565-0090, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E565-0090 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E565-0090
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E565-0090
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E565-0090 available by request