E570-0457 Screening compound: N-benzyl-N-ethyl-2-(N-methyl1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)acetamide

E570-0457 Screening compound: N-benzyl-N-ethyl-2-(N-methyl1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)acetamide
E570-0457 Screening compound: N-benzyl-N-ethyl-2-(N-methyl1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-0457
N-benzyl-N-ethyl-2-(N-methyl1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-0457

Molecular Formula

C25H31N3O4S (C25 H31 N3 O4 S)

Compound Name

N-benzyl-N-ethyl-2-(N-methyl1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)acetamide

IUPAC name

N-benzyl-N-ethyl-2-(N-methyl1-cyclopropanecarbonyl-2-methyl-23-dihydro-1H-indole-5-sulfonamido)acetamide

SMILES

CCN(Cc1ccccc1)C(CN(C)S(c(cc1)cc(CC2C)c1N2C(C1CC1)=O)(=O)=O)=O

InChI

InChI=1S/C25H31N3O4S/c1-4-27(16-19-8-6-5-7-9-19)24(29)17-26(3)33(31,32)22-12-13-23-21(15-22)14-18(2)28(23)25(30)20-10-11-20/h5-9,12-13,15,18,20H,4,10-11,14,16-17H2,1-3H3/t18-/m1/s1

InChI Key

RRBUSJNPNXMNGA-GOSISDBHSA-N

MDL Number (MFCD)

MFCD14899515

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.6

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.097

Distribution Coefficient, logD

3.097

Water Solubility, LogSw

-3.51

Polar Surface Area

63.623

Acid Dissociation Constant (pKa)

21.65

Base Dissociation Constant (pKb)

-1.63

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

E570-0457 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

SH2 Library (10483 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with E570-0457 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-0457?
Check Price and Availability of E570-0457, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E570-0457 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-0457
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-0457
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-0457 available by request