E570-1458 Screening compound: 1-(2-methyl-5-{[4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one

E570-1458 Screening compound: 1-(2-methyl-5-{[4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one
E570-1458 Screening compound: 1-(2-methyl-5-{[4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-1458
1-(2-methyl-5-{[4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-1458

Molecular Formula

C22H32N4O4S (C22 H32 N4 O4 S)

Compound Name

1-(2-methyl-5-{[4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one

IUPAC name

1-(2-methyl-5-{[4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]sulfonyl}-23-dihydro-1H-indol-1-yl)ethan-1-one

SMILES

CC(C1)N(C(C)=O)c(cc2)c1cc2S(N(CC1)CCC1C(N1CCN(C)CC1)=O)(=O)=O

InChI

InChI=1S/C22H32N4O4S/c1-16-14-19-15-20(4-5-21(19)26(16)17(2)27)31(29,30)25-8-6-18(7-9-25)22(28)24-12-10-23(3)11-13-24/h4-5,15-16,18H,6-14H2,1-3H3/t16-/m1/s1

InChI Key

SGZLTXIMJFSVGI-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD14899654

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.972

Distribution Coefficient, logD

0.624

Water Solubility, LogSw

-2.44

Polar Surface Area

67.431

Acid Dissociation Constant (pKa)

23.37

Base Dissociation Constant (pKb)

7.49

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

63.60

E570-1458 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E570-1458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-1458?
Check Price and Availability of E570-1458, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E570-1458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-1458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-1458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-1458 available by request