E570-1637 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(5-methylpyridin-2-yl)piperidine-3-carboxamide

E570-1637 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(5-methylpyridin-2-yl)piperidine-3-carboxamide
E570-1637 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(5-methylpyridin-2-yl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-1637
1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(5-methylpyridin-2-yl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-1637

Molecular Formula

C23H28N4O4S (C23 H28 N4 O4 S)

Compound Name

1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(5-methylpyridin-2-yl)piperidine-3-carboxamide

IUPAC name

1-[(1-acetyl-2-methyl-23-dihydro-1H-indol-5-yl)sulfonyl]-N-(5-methylpyridin-2-yl)piperidine-3-carboxamide

SMILES

CC(C1)N(C(C)=O)c(cc2)c1cc2S(N(CCC1)CC1C(Nc1ncc(C)cc1)=O)(=O)=O

InChI

InChI=1S/C23H28N4O4S/c1-15-6-9-22(24-13-15)25-23(29)18-5-4-10-26(14-18)32(30,31)20-7-8-21-19(12-20)11-16(2)27(21)17(3)28/h6-9,12-13,16,18H,4-5,10-11,14H2,1-3H3,(H,24,25,29)

InChI Key

VDQOLLQBSQVLPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899692

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.57

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.554

Distribution Coefficient, logD

2.550

Water Solubility, LogSw

-2.87

Polar Surface Area

80.036

Acid Dissociation Constant (pKa)

9.43

Base Dissociation Constant (pKb)

4.33

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

43.50

E570-1637 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • Epigenetic
Structure:
  • Mimetics
Targets:
  • Others
  • Kinases

References: we are preparing a list of scientific research reports with E570-1637 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-1637?
Check Price and Availability of E570-1637, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E570-1637 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-1637
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-1637
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-1637 available by request