E570-1648 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3-chlorophenyl)piperidine-3-carboxamide

E570-1648 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3-chlorophenyl)piperidine-3-carboxamide
E570-1648 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3-chlorophenyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-1648
1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3-chlorophenyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-1648

Molecular Formula

C23H26ClN3O4S (C23 H26 ClN3 O4 S)

Compound Name

1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3-chlorophenyl)piperidine-3-carboxamide

IUPAC name

1-[(1-acetyl-2-methyl-23-dihydro-1H-indol-5-yl)sulfonyl]-N-(3-chlorophenyl)piperidine-3-carboxamide

SMILES

CC(C1)N(C(C)=O)c(cc2)c1cc2S(N(CCC1)CC1C(Nc1cccc(Cl)c1)=O)(=O)=O

InChI

InChI=1S/C23H26ClN3O4S/c1-15-11-18-12-21(8-9-22(18)27(15)16(2)28)32(30,31)26-10-4-5-17(14-26)23(29)25-20-7-3-6-19(24)13-20/h3,6-9,12-13,15,17H,4-5,10-11,14H2,1-2H3,(H,25,29)

InChI Key

HUAWISZIUATZGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899697

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.222

Distribution Coefficient, logD

3.219

Water Solubility, LogSw

-3.64

Polar Surface Area

70.331

Acid Dissociation Constant (pKa)

9.58

Base Dissociation Constant (pKb)

-1.45

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

39.10

E570-1648 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antiviral Annotated Library (21441 compounds)

CNS targets activity set (6557 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E570-1648 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-1648?
Check Price and Availability of E570-1648, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E570-1648 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-1648
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-1648
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-1648 available by request