E570-1721 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3,4-dimethylphenyl)piperidine-3-carboxamide

E570-1721 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3,4-dimethylphenyl)piperidine-3-carboxamide
E570-1721 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3,4-dimethylphenyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-1721
1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3,4-dimethylphenyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-1721

Molecular Formula

C25H31N3O4S (C25 H31 N3 O4 S)

Compound Name

1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3,4-dimethylphenyl)piperidine-3-carboxamide

IUPAC name

1-[(1-acetyl-2-methyl-23-dihydro-1H-indol-5-yl)sulfonyl]-N-(34-dimethylphenyl)piperidine-3-carboxamide

SMILES

CC(C1)N(C(C)=O)c(cc2)c1cc2S(N(CCC1)CC1C(Nc1cc(C)c(C)cc1)=O)(=O)=O

InChI

InChI=1S/C25H31N3O4S/c1-16-7-8-22(12-17(16)2)26-25(30)20-6-5-11-27(15-20)33(31,32)23-9-10-24-21(14-23)13-18(3)28(24)19(4)29/h7-10,12,14,18,20H,5-6,11,13,15H2,1-4H3,(H,26,30)

InChI Key

HYVOUEIJVDYBJE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899718

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.6

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.456

Distribution Coefficient, logD

3.456

Water Solubility, LogSw

-3.89

Polar Surface Area

70.331

Acid Dissociation Constant (pKa)

11.51

Base Dissociation Constant (pKb)

0.49

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

44.00

E570-1721 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Epigenetic
Structure:
  • Mimetics
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with E570-1721 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-1721?
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What is the minimum amount of E570-1721 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-1721
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-1721
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-1721 available by request