E570-1740 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-[3-(methylsulfanyl)phenyl]piperidine-3-carboxamide

E570-1740 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-[3-(methylsulfanyl)phenyl]piperidine-3-carboxamide
E570-1740 Screening compound: 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-[3-(methylsulfanyl)phenyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-1740
1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-[3-(methylsulfanyl)phenyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-1740

Molecular Formula

C24H29N3O4S2 (C24 H29 N3 O4 S2)

Compound Name

1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-[3-(methylsulfanyl)phenyl]piperidine-3-carboxamide

IUPAC name

1-[(1-acetyl-2-methyl-23-dihydro-1H-indol-5-yl)sulfonyl]-N-[3-(methylsulfanyl)phenyl]piperidine-3-carboxamide

SMILES

CC(C1)N(C(C)=O)c(cc2)c1cc2S(N(CCC1)CC1C(Nc1cc(SC)ccc1)=O)(=O)=O

InChI

InChI=1S/C24H29N3O4S2/c1-16-12-19-13-22(9-10-23(19)27(16)17(2)28)33(30,31)26-11-5-6-18(15-26)24(29)25-20-7-4-8-21(14-20)32-3/h4,7-10,13-14,16,18H,5-6,11-12,15H2,1-3H3,(H,25,29)

InChI Key

SQGXIUZHNLIGTQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899722

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.64

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.929

Distribution Coefficient, logD

2.929

Water Solubility, LogSw

-3.52

Polar Surface Area

70.331

Acid Dissociation Constant (pKa)

11.27

Base Dissociation Constant (pKb)

-0.55

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

41.70

E570-1740 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E570-1740 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-1740?
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What is the minimum amount of E570-1740 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-1740
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-1740
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-1740 available by request