E570-2708 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(3-methylpyridin-2-yl)-3-phenylpropanamide

E570-2708 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(3-methylpyridin-2-yl)-3-phenylpropanamide
E570-2708 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(3-methylpyridin-2-yl)-3-phenylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-2708
2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(3-methylpyridin-2-yl)-3-phenylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-2708

Molecular Formula

C26H28N4O4S (C26 H28 N4 O4 S)

Compound Name

2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(3-methylpyridin-2-yl)-3-phenylpropanamide

IUPAC name

2-(1-acetyl-2-methyl-23-dihydro-1H-indole-5-sulfonamido)-N-(3-methylpyridin-2-yl)-3-phenylpropanamide

SMILES

CC(C1)N(C(C)=O)c(cc2)c1cc2S(NC(Cc1ccccc1)C(Nc1ncccc1C)=O)(=O)=O

InChI

InChI=1S/C26H28N4O4S/c1-17-8-7-13-27-25(17)28-26(32)23(15-20-9-5-4-6-10-20)29-35(33,34)22-11-12-24-21(16-22)14-18(2)30(24)19(3)31/h4-13,16,18,23,29H,14-15H2,1-3H3,(H,27,28,32)

InChI Key

FVPYWDZHSIYKPI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899943

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.6

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.683

Distribution Coefficient, logD

3.672

Water Solubility, LogSw

-3.98

Polar Surface Area

89.976

Acid Dissociation Constant (pKa)

9.02

Base Dissociation Constant (pKb)

3.60

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

26.90

E570-2708 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SH2 Library (10483 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Proteases
  • Kinases
  • GPCR
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E570-2708 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-2708?
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What is the minimum amount of E570-2708 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-2708
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-2708
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-2708 available by request