E570-2874 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(4-methylphenyl)-3-phenylpropanamide

E570-2874 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(4-methylphenyl)-3-phenylpropanamide
E570-2874 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(4-methylphenyl)-3-phenylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-2874
2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(4-methylphenyl)-3-phenylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-2874

Molecular Formula

C27H29N3O4S (C27 H29 N3 O4 S)

Compound Name

2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(4-methylphenyl)-3-phenylpropanamide

IUPAC name

2-(1-acetyl-2-methyl-23-dihydro-1H-indole-5-sulfonamido)-N-(4-methylphenyl)-3-phenylpropanamide

SMILES

CC(C1)N(C(C)=O)c(cc2)c1cc2S(NC(Cc1ccccc1)C(Nc1ccc(C)cc1)=O)(=O)=O

InChI

InChI=1S/C27H29N3O4S/c1-18-9-11-23(12-10-18)28-27(32)25(16-21-7-5-4-6-8-21)29-35(33,34)24-13-14-26-22(17-24)15-19(2)30(26)20(3)31/h4-14,17,19,25,29H,15-16H2,1-3H3,(H,28,32)

InChI Key

LCJQUUFGTXZCBO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899953

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.61

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.356

Distribution Coefficient, logD

4.355

Water Solubility, LogSw

-4.30

Polar Surface Area

80.289

Acid Dissociation Constant (pKa)

11.01

Base Dissociation Constant (pKb)

0.01

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

25.90

E570-2874 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E570-2874 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-2874?
Check Price and Availability of E570-2874, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E570-2874 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-2874
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-2874
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-2874 available by request