E570-2888 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-phenyl-N-(pyridin-2-yl)propanamide

E570-2888 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-phenyl-N-(pyridin-2-yl)propanamide
E570-2888 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-phenyl-N-(pyridin-2-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-2888
2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-phenyl-N-(pyridin-2-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-2888

Molecular Formula

C25H26N4O4S (C25 H26 N4 O4 S)

Compound Name

2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-phenyl-N-(pyridin-2-yl)propanamide

IUPAC name

2-(1-acetyl-2-methyl-23-dihydro-1H-indole-5-sulfonamido)-3-phenyl-N-(pyridin-2-yl)propanamide

SMILES

CC(C1)N(C(C)=O)c(cc2)c1cc2S(NC(Cc1ccccc1)C(Nc1ncccc1)=O)(=O)=O

InChI

InChI=1S/C25H26N4O4S/c1-17-14-20-16-21(11-12-23(20)29(17)18(2)30)34(32,33)28-22(15-19-8-4-3-5-9-19)25(31)27-24-10-6-7-13-26-24/h3-13,16-17,22,28H,14-15H2,1-2H3,(H,26,27,31)

InChI Key

JHDCYNNQYYSRFM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899956

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.57

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.398

Distribution Coefficient, logD

3.392

Water Solubility, LogSw

-3.95

Polar Surface Area

89.904

Acid Dissociation Constant (pKa)

9.26

Base Dissociation Constant (pKb)

2.84

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

24.00

E570-2888 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SH2 Library (10483 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Proteases
  • Kinases
  • GPCR
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E570-2888 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-2888?
Check Price and Availability of E570-2888, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E570-2888 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-2888
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-2888
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-2888 available by request