E570-4078 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(2,3-dimethylphenyl)-3-methylbutanamide

E570-4078 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(2,3-dimethylphenyl)-3-methylbutanamide
E570-4078 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(2,3-dimethylphenyl)-3-methylbutanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-4078
2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(2,3-dimethylphenyl)-3-methylbutanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-4078

Molecular Formula

C24H31N3O4S (C24 H31 N3 O4 S)

Compound Name

2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-N-(2,3-dimethylphenyl)-3-methylbutanamide

IUPAC name

2-(1-acetyl-2-methyl-23-dihydro-1H-indole-5-sulfonamido)-N-(23-dimethylphenyl)-3-methylbutanamide

SMILES

CC(C)C(C(Nc1c(C)c(C)ccc1)=O)NS(c(cc1)cc(CC2C)c1N2C(C)=O)(=O)=O

InChI

InChI=1S/C24H31N3O4S/c1-14(2)23(24(29)25-21-9-7-8-15(3)17(21)5)26-32(30,31)20-10-11-22-19(13-20)12-16(4)27(22)18(6)28/h7-11,13-14,16,23,26H,12H2,1-6H3,(H,25,29)

InChI Key

GYJIIKLIGXXNRN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899974

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.978

Distribution Coefficient, logD

3.978

Water Solubility, LogSw

-4.05

Polar Surface Area

79.584

Acid Dissociation Constant (pKa)

10.72

Base Dissociation Constant (pKb)

-0.46

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

41.70

E570-4078 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with E570-4078 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-4078?
Check Price and Availability of E570-4078, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E570-4078 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-4078
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-4078
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-4078 available by request