E589-5146 Screening compound: N-[(2-chlorophenyl)methyl]-1-[(2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]piperidine-3-carboxamide

E589-5146 Screening compound: N-[(2-chlorophenyl)methyl]-1-[(2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]piperidine-3-carboxamide
E589-5146 Screening compound: N-[(2-chlorophenyl)methyl]-1-[(2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E589-5146
N-[(2-chlorophenyl)methyl]-1-[(2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E589-5146

Molecular Formula

C22H22ClN3O4S (C22 H22 ClN3 O4 S)

Compound Name

N-[(2-chlorophenyl)methyl]-1-[(2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-[(2-chlorophenyl)methyl]-1-[(2-oxo-12-dihydroquinolin-6-yl)sulfonyl]piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1S(c(cc1)cc(C=C2)c1NC2=O)(=O)=O)NCc(cccc1)c1Cl

InChI

InChI=1S/C22H22ClN3O4S/c23-19-6-2-1-4-16(19)13-24-22(28)17-5-3-11-26(14-17)31(29,30)18-8-9-20-15(12-18)7-10-21(27)25-20/h1-2,4,6-10,12,17H,3,5,11,13-14H2,(H,24,28)(H,25,27)/t17-/m0/s1

InChI Key

PGVNJYWMLKDEDP-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD14901167

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.95

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.858

Distribution Coefficient, logD

2.851

Water Solubility, LogSw

-3.47

Polar Surface Area

81.117

Acid Dissociation Constant (pKa)

9.24

Base Dissociation Constant (pKb)

-3.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.30

E589-5146 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

GPCR Targeted Library (31838 compounds)

PLpro Library (6343 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Immune system
  • animal
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with E589-5146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E589-5146?
Check Price and Availability of E589-5146, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E589-5146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E589-5146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E589-5146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E589-5146 available by request