E591-0924 Screening compound: 3-[6-(morpholin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one

E591-0924 Screening compound: 3-[6-(morpholin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one
E591-0924 Screening compound: 3-[6-(morpholin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E591-0924
3-[6-(morpholin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E591-0924

Molecular Formula

C22H27N7O2 (C22 H27 N7 O2)

Compound Name

3-[6-(morpholin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one

IUPAC name

3-[6-(morpholin-4-yl)-[124]triazolo[43-b]pyridazin-3-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one

SMILES

O=C(CCc1nnc(cc2)n1nc2N1CCOCC1)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C22H27N7O2/c30-22(28-12-10-26(11-13-28)18-4-2-1-3-5-18)9-8-20-24-23-19-6-7-21(25-29(19)20)27-14-16-31-17-15-27/h1-7H,8-17H2

InChI Key

PIGRIRCKNWHGRZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14901722

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.208

Distribution Coefficient, logD

1.208

Water Solubility, LogSw

-1.65

Polar Surface Area

63.850

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

6.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

E591-0924 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E591-0924 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E591-0924?
Check Price and Availability of E591-0924, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E591-0924 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E591-0924
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E591-0924
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E591-0924 available by request