E612-1458 Screening compound: N-(3,4-dimethoxyphenyl)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)acetamide

E612-1458 Screening compound: N-(3,4-dimethoxyphenyl)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)acetamide
E612-1458 Screening compound: N-(3,4-dimethoxyphenyl)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E612-1458
N-(3,4-dimethoxyphenyl)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E612-1458

Molecular Formula

C18H18N2O4 (C18 H18 N2 O4)

Compound Name

N-(3,4-dimethoxyphenyl)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)acetamide

IUPAC name

N-(34-dimethoxyphenyl)-2-(1-oxo-23-dihydro-1H-isoindol-2-yl)acetamide

SMILES

COc(ccc(NC(CN(Cc1c2cccc1)C2=O)=O)c1)c1OC

InChI

InChI=1S/C18H18N2O4/c1-23-15-8-7-13(9-16(15)24-2)19-17(21)11-20-10-12-5-3-4-6-14(12)18(20)22/h3-9H,10-11H2,1-2H3,(H,19,21)

InChI Key

DNSGJUQHHMHPAB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14903742

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.35

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.917

Distribution Coefficient, logD

1.917

Water Solubility, LogSw

-3.00

Polar Surface Area

55.295

Acid Dissociation Constant (pKa)

11.48

Base Dissociation Constant (pKb)

2.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

E612-1458 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E612-1458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E612-1458?
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What is the minimum amount of E612-1458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E612-1458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E612-1458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E612-1458 available by request