E626-0176 Screening compound: 1-ethyl-4-{1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carbonyl}piperazine

E626-0176 Screening compound: 1-ethyl-4-{1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carbonyl}piperazine
E626-0176 Screening compound: 1-ethyl-4-{1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E626-0176
1-ethyl-4-{1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E626-0176

Molecular Formula

C22H27FN6OS (C22 H27 FN6 OS)

Compound Name

1-ethyl-4-{1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carbonyl}piperazine

IUPAC name

1-ethyl-4-{1-[6-(4-fluorophenyl)imidazo[21-b][134]thiadiazol-2-yl]piperidine-4-carbonyl}piperazine

SMILES

CCN(CC1)CCN1C(C(CC1)CCN1c(s1)nn2c1nc(-c(cc1)ccc1F)c2)=O

InChI

InChI=1S/C22H27FN6OS/c1-2-26-11-13-27(14-12-26)20(30)17-7-9-28(10-8-17)22-25-29-15-19(24-21(29)31-22)16-3-5-18(23)6-4-16/h3-6,15,17H,2,7-14H2,1H3

InChI Key

YMTAECRQVDHYRL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14904747

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.101

Distribution Coefficient, logD

2.662

Water Solubility, LogSw

-2.81

Polar Surface Area

44.711

Acid Dissociation Constant (pKa)

21.73

Base Dissociation Constant (pKb)

7.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

E626-0176 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E626-0176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E626-0176?
Check Price and Availability of E626-0176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E626-0176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E626-0176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E626-0176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E626-0176 available by request