E626-0216 Screening compound: N-(3,5-dimethoxyphenyl)-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carboxamide

E626-0216 Screening compound: N-(3,5-dimethoxyphenyl)-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carboxamide
E626-0216 Screening compound: N-(3,5-dimethoxyphenyl)-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E626-0216
N-(3,5-dimethoxyphenyl)-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E626-0216

Molecular Formula

C24H24FN5O3S (C24 H24 FN5 O3 S)

Compound Name

N-(3,5-dimethoxyphenyl)-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-4-carboxamide

IUPAC name

N-(35-dimethoxyphenyl)-1-[6-(4-fluorophenyl)imidazo[21-b][134]thiadiazol-2-yl]piperidine-4-carboxamide

SMILES

COc1cc(NC(C(CC2)CCN2c(s2)nn3c2nc(-c(cc2)ccc2F)c3)=O)cc(OC)c1

InChI

InChI=1S/C24H24FN5O3S/c1-32-19-11-18(12-20(13-19)33-2)26-22(31)16-7-9-29(10-8-16)24-28-30-14-21(27-23(30)34-24)15-3-5-17(25)6-4-15/h3-6,11-14,16H,7-10H2,1-2H3,(H,26,31)

InChI Key

BNZSRVAUJQZCMO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14904759

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.476

Distribution Coefficient, logD

4.475

Water Solubility, LogSw

-4.11

Polar Surface Area

62.705

Acid Dissociation Constant (pKa)

10.12

Base Dissociation Constant (pKb)

3.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

E626-0216 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E626-0216 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E626-0216?
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What is the minimum amount of E626-0216 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E626-0216
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E626-0216
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E626-0216 available by request