E626-0602 Screening compound: 1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide

E626-0602 Screening compound: 1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide
E626-0602 Screening compound: 1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E626-0602
1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E626-0602

Molecular Formula

C26H29N5O2S (C26 H29 N5 O2 S)

Compound Name

1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide

IUPAC name

1-[6-(4-methoxyphenyl)imidazo[21-b][134]thiadiazol-2-yl]-N-(246-trimethylphenyl)piperidine-4-carboxamide

SMILES

Cc(cc1C)cc(C)c1NC(C(CC1)CCN1c(s1)nn2c1nc(-c(cc1)ccc1OC)c2)=O

InChI

InChI=1S/C26H29N5O2S/c1-16-13-17(2)23(18(3)14-16)28-24(32)20-9-11-30(12-10-20)26-29-31-15-22(27-25(31)34-26)19-5-7-21(33-4)8-6-19/h5-8,13-15,20H,9-12H2,1-4H3,(H,28,32)

InChI Key

FILYWNDTCFBDMA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14904956

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.61

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.994

Distribution Coefficient, logD

4.994

Water Solubility, LogSw

-4.50

Polar Surface Area

53.765

Acid Dissociation Constant (pKa)

11.48

Base Dissociation Constant (pKb)

3.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

E626-0602 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E626-0602 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E626-0602?
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What is the minimum amount of E626-0602 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E626-0602
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E626-0602
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E626-0602 available by request