E626-0810 Screening compound: 1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-[3-(propylsulfanyl)propyl]piperidine-3-carboxamide

E626-0810 Screening compound: 1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-[3-(propylsulfanyl)propyl]piperidine-3-carboxamide
E626-0810 Screening compound: 1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-[3-(propylsulfanyl)propyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E626-0810
1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-[3-(propylsulfanyl)propyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E626-0810

Molecular Formula

C23H31N5O2S2 (C23 H31 N5 O2 S2)

Compound Name

1-[6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-[3-(propylsulfanyl)propyl]piperidine-3-carboxamide

IUPAC name

1-[6-(4-methoxyphenyl)imidazo[21-b][134]thiadiazol-2-yl]-N-[3-(propylsulfanyl)propyl]piperidine-3-carboxamide

SMILES

CCCSCCCNC(C(CCC1)CN1c(s1)nn2c1nc(-c(cc1)ccc1OC)c2)=O

InChI

InChI=1S/C23H31N5O2S2/c1-3-13-31-14-5-11-24-21(29)18-6-4-12-27(15-18)23-26-28-16-20(25-22(28)32-23)17-7-9-19(30-2)10-8-17/h7-10,16,18H,3-6,11-15H2,1-2H3,(H,24,29)/t18-/m0/s1

InChI Key

YFPKHWAJXZMLNA-SFHVURJKSA-N

MDL Number (MFCD)

MFCD14905056

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

473.66

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.110

Distribution Coefficient, logD

4.110

Water Solubility, LogSw

-3.87

Polar Surface Area

56.530

Acid Dissociation Constant (pKa)

15.00

Base Dissociation Constant (pKb)

3.63

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.20

E626-0810 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Human Proteases Annotated Library (2868 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E626-0810 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E626-0810?
Check Price and Availability of E626-0810, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E626-0810 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E626-0810
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E626-0810
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E626-0810 available by request