E626-0841 Screening compound: 1-[6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-3-(piperidine-1-carbonyl)piperidine

E626-0841 Screening compound: 1-[6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-3-(piperidine-1-carbonyl)piperidine
E626-0841 Screening compound: 1-[6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-3-(piperidine-1-carbonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound E626-0841
1-[6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-3-(piperidine-1-carbonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E626-0841

Molecular Formula

C22H27N5OS (C22 H27 N5 OS)

Compound Name

1-[6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-3-(piperidine-1-carbonyl)piperidine

IUPAC name

1-[6-(4-methylphenyl)imidazo[21-b][134]thiadiazol-2-yl]-3-(piperidine-1-carbonyl)piperidine

SMILES

Cc(cc1)ccc1-c1cn2nc(N(CCC3)CC3C(N3CCCCC3)=O)sc2n1

InChI

InChI=1S/C22H27N5OS/c1-16-7-9-17(10-8-16)19-15-27-21(23-19)29-22(24-27)26-13-5-6-18(14-26)20(28)25-11-3-2-4-12-25/h7-10,15,18H,2-6,11-14H2,1H3/t18-/m0/s1

InChI Key

YJNDYQSTISRRSK-SFHVURJKSA-N

MDL Number (MFCD)

MFCD14905068

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.56

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.262

Distribution Coefficient, logD

4.261

Water Solubility, LogSw

-4.04

Polar Surface Area

41.108

Acid Dissociation Constant (pKa)

22.72

Base Dissociation Constant (pKb)

4.59

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

E626-0841 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E626-0841 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E626-0841?
Check Price and Availability of E626-0841, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E626-0841 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E626-0841
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E626-0841
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E626-0841 available by request