E629-0086 Screening compound: N-cyclopropyl-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide

E629-0086 Screening compound: N-cyclopropyl-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide
E629-0086 Screening compound: N-cyclopropyl-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E629-0086
N-cyclopropyl-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E629-0086

Molecular Formula

C17H16N2OS (C17 H16 N2 OS)

Compound Name

N-cyclopropyl-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide

IUPAC name

N-cyclopropyl-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide

SMILES

O=C(Cn(c(-c1cccs1)c1)c2c1cccc2)NC1CC1

InChI

InChI=1S/C17H16N2OS/c20-17(18-13-7-8-13)11-19-14-5-2-1-4-12(14)10-15(19)16-6-3-9-21-16/h1-6,9-10,13H,7-8,11H2,(H,18,20)

InChI Key

LSWNIWMMOCEVRW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27600619

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

296.39

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

3.726

Distribution Coefficient, logD

3.726

Water Solubility, LogSw

-4.12

Polar Surface Area

25.967

Acid Dissociation Constant (pKa)

13.43

Base Dissociation Constant (pKb)

1.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

E629-0086 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with E629-0086 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E629-0086?
Check Price and Availability of E629-0086, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E629-0086 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E629-0086
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E629-0086
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E629-0086 available by request