E629-1460 Screening compound: 2-[5-fluoro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-[(pyridin-2-yl)methyl]acetamide

E629-1460 Screening compound: 2-[5-fluoro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-[(pyridin-2-yl)methyl]acetamide
E629-1460 Screening compound: 2-[5-fluoro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-[(pyridin-2-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E629-1460
2-[5-fluoro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-[(pyridin-2-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E629-1460

Molecular Formula

C20H16FN3OS (C20 H16 FN3 OS)

Compound Name

2-[5-fluoro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-[(pyridin-2-yl)methyl]acetamide

IUPAC name

2-[5-fluoro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-[(pyridin-2-yl)methyl]acetamide

SMILES

O=C(Cn(c(-c1cccs1)c1)c(cc2)c1cc2F)NCc1ncccc1

InChI

InChI=1S/C20H16FN3OS/c21-15-6-7-17-14(10-15)11-18(19-5-3-9-26-19)24(17)13-20(25)23-12-16-4-1-2-8-22-16/h1-11H,12-13H2,(H,23,25)

InChI Key

ASWNTIZLYDEFOJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27600690

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.012

Distribution Coefficient, logD

4.011

Water Solubility, LogSw

-4.03

Polar Surface Area

35.454

Acid Dissociation Constant (pKa)

12.60

Base Dissociation Constant (pKb)

4.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

E629-1460 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E629-1460 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E629-1460?
Check Price and Availability of E629-1460, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E629-1460 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E629-1460
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E629-1460
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E629-1460 available by request