E629-1746 Screening compound: 2-[5-chloro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-cyclopropylacetamide

E629-1746 Screening compound: 2-[5-chloro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-cyclopropylacetamide
E629-1746 Screening compound: 2-[5-chloro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-cyclopropylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E629-1746
2-[5-chloro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-cyclopropylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E629-1746

Molecular Formula

C17H15ClN2OS (C17 H15 ClN2 OS)

Compound Name

2-[5-chloro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-cyclopropylacetamide

IUPAC name

2-[5-chloro-2-(thiophen-2-yl)-1H-indol-1-yl]-N-cyclopropylacetamide

SMILES

O=C(Cn(c(-c1cccs1)c1)c(cc2)c1cc2Cl)NC1CC1

InChI

InChI=1S/C17H15ClN2OS/c18-12-3-6-14-11(8-12)9-15(16-2-1-7-22-16)20(14)10-17(21)19-13-4-5-13/h1-3,6-9,13H,4-5,10H2,(H,19,21)

InChI Key

QZACJLFFWKOTOY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27600776

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

330.84

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.455

Distribution Coefficient, logD

4.455

Water Solubility, LogSw

-4.50

Polar Surface Area

25.967

Acid Dissociation Constant (pKa)

13.43

Base Dissociation Constant (pKb)

1.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

E629-1746 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Cardiovascular Library (22201 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cardiovascular
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E629-1746 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E629-1746?
Check Price and Availability of E629-1746, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E629-1746 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E629-1746
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E629-1746
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E629-1746 available by request