E634-1480 Screening compound: 2-({[4-(5-chloro-2-methoxyphenyl)-5-{4-methyl-4H-furo[3,2-b]pyrrol-5-yl}-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)pyridine

E634-1480 Screening compound: 2-({[4-(5-chloro-2-methoxyphenyl)-5-{4-methyl-4H-furo[3,2-b]pyrrol-5-yl}-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)pyridine
E634-1480 Screening compound: 2-({[4-(5-chloro-2-methoxyphenyl)-5-{4-methyl-4H-furo[3,2-b]pyrrol-5-yl}-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound E634-1480
2-({[4-(5-chloro-2-methoxyphenyl)-5-{4-methyl-4H-furo[3,2-b]pyrrol-5-yl}-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E634-1480

Molecular Formula

C22H18ClN5O2S (C22 H18 ClN5 O2 S)

Compound Name

2-({[4-(5-chloro-2-methoxyphenyl)-5-{4-methyl-4H-furo[3,2-b]pyrrol-5-yl}-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)pyridine

IUPAC name

2-({[4-(5-chloro-2-methoxyphenyl)-5-{4-methyl-4H-furo[32-b]pyrrol-5-yl}-4H-124-triazol-3-yl]sulfanyl}methyl)pyridine

SMILES

Cn1c(-c(n2-c(cc(cc3)Cl)c3OC)nnc2SCc2ncccc2)cc2c1cco2

InChI

InChI=1S/C22H18ClN5O2S/c1-27-16-8-10-30-20(16)12-18(27)21-25-26-22(31-13-15-5-3-4-9-24-15)28(21)17-11-14(23)6-7-19(17)29-2/h3-12H,13H2,1-2H3

InChI Key

VLBIOUMBSWRKOR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14905852

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.94

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.913

Distribution Coefficient, logD

3.911

Water Solubility, LogSw

-4.29

Polar Surface Area

51.593

Acid Dissociation Constant (pKa)

25.77

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

E634-1480 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with E634-1480 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E634-1480?
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What is the minimum amount of E634-1480 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E634-1480
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E634-1480
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E634-1480 available by request