E642-0266 Screening compound: 4-[({3-[(3-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}sulfanyl)methyl]-N-(4-methylcyclohexyl)benzamide

E642-0266 Screening compound: 4-[({3-[(3-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}sulfanyl)methyl]-N-(4-methylcyclohexyl)benzamide
E642-0266 Screening compound: 4-[({3-[(3-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}sulfanyl)methyl]-N-(4-methylcyclohexyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E642-0266
4-[({3-[(3-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}sulfanyl)methyl]-N-(4-methylcyclohexyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E642-0266

Molecular Formula

C28H29FN4OS (C28 H29 FN4 OS)

Compound Name

4-[({3-[(3-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}sulfanyl)methyl]-N-(4-methylcyclohexyl)benzamide

IUPAC name

4-[({3-[(3-fluorophenyl)methyl]-3H-imidazo[45-b]pyridin-2-yl}sulfanyl)methyl]-N-(4-methylcyclohexyl)benzamide

SMILES

CC(CC1)CCC1NC(c1ccc(CSc(n2Cc3cc(F)ccc3)nc3c2nccc3)cc1)=O

InChI

InChI=1S/C28H29FN4OS/c1-19-7-13-24(14-8-19)31-27(34)22-11-9-20(10-12-22)18-35-28-32-25-6-3-15-30-26(25)33(28)17-21-4-2-5-23(29)16-21/h2-6,9-12,15-16,19,24H,7-8,13-14,17-18H2,1H3,(H,31,34)

InChI Key

LGDQBBZQUVTULG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14906636

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.63

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.288

Distribution Coefficient, logD

6.288

Water Solubility, LogSw

-5.50

Polar Surface Area

44.523

Acid Dissociation Constant (pKa)

14.07

Base Dissociation Constant (pKb)

4.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

E642-0266 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Epigenetics Focused Set (26518 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with E642-0266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E642-0266?
Check Price and Availability of E642-0266, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E642-0266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E642-0266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E642-0266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E642-0266 available by request