E643-0436 Screening compound: N-(3-chloro-4-methylphenyl)-2-(2-{[(4-methylphenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)butanamide

E643-0436 Screening compound: N-(3-chloro-4-methylphenyl)-2-(2-{[(4-methylphenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)butanamide
E643-0436 Screening compound: N-(3-chloro-4-methylphenyl)-2-(2-{[(4-methylphenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E643-0436
N-(3-chloro-4-methylphenyl)-2-(2-{[(4-methylphenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E643-0436

Molecular Formula

C25H25ClN4OS (C25 H25 ClN4 OS)

Compound Name

N-(3-chloro-4-methylphenyl)-2-(2-{[(4-methylphenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)butanamide

IUPAC name

N-(3-chloro-4-methylphenyl)-2-(2-{[(4-methylphenyl)methyl]sulfanyl}-3H-imidazo[45-b]pyridin-3-yl)butanamide

SMILES

CCC(C(Nc1cc(Cl)c(C)cc1)=O)n1c(SCc2ccc(C)cc2)nc2cccnc12

InChI

InChI=1S/C25H25ClN4OS/c1-4-22(24(31)28-19-12-9-17(3)20(26)14-19)30-23-21(6-5-13-27-23)29-25(30)32-15-18-10-7-16(2)8-11-18/h5-14,22H,4,15H2,1-3H3,(H,28,31)/t22-/m0/s1

InChI Key

DCBZXGNMXGWXMQ-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD14907045

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.02

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.382

Distribution Coefficient, logD

6.381

Water Solubility, LogSw

-6.19

Polar Surface Area

44.027

Acid Dissociation Constant (pKa)

10.00

Base Dissociation Constant (pKb)

2.48

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

24.00

E643-0436 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E643-0436 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E643-0436?
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What is the minimum amount of E643-0436 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E643-0436
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E643-0436
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E643-0436 available by request