E643-0800 Screening compound: N-(3,5-dimethylphenyl)-2-(2-{[(3-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)acetamide

E643-0800 Screening compound: N-(3,5-dimethylphenyl)-2-(2-{[(3-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)acetamide
E643-0800 Screening compound: N-(3,5-dimethylphenyl)-2-(2-{[(3-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E643-0800
N-(3,5-dimethylphenyl)-2-(2-{[(3-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E643-0800

Molecular Formula

C23H21FN4OS (C23 H21 FN4 OS)

Compound Name

N-(3,5-dimethylphenyl)-2-(2-{[(3-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-b]pyridin-3-yl)acetamide

IUPAC name

N-(35-dimethylphenyl)-2-(2-{[(3-fluorophenyl)methyl]sulfanyl}-3H-imidazo[45-b]pyridin-3-yl)acetamide

SMILES

Cc1cc(NC(Cn2c(SCc3cc(F)ccc3)nc3c2nccc3)=O)cc(C)c1

InChI

InChI=1S/C23H21FN4OS/c1-15-9-16(2)11-19(10-15)26-21(29)13-28-22-20(7-4-8-25-22)27-23(28)30-14-17-5-3-6-18(24)12-17/h3-12H,13-14H2,1-2H3,(H,26,29)

InChI Key

YGJSMIABYSHULP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14907076

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.208

Distribution Coefficient, logD

5.208

Water Solubility, LogSw

-5.03

Polar Surface Area

43.533

Acid Dissociation Constant (pKa)

12.81

Base Dissociation Constant (pKb)

3.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

E643-0800 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E643-0800 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E643-0800?
Check Price and Availability of E643-0800, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E643-0800 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E643-0800
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E643-0800
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E643-0800 available by request